कार्बनिक रसायन विज्ञान: वर्तमान अनुसंधान
खुला एक्सेस

अमूर्त

Synthesis and Characterization of Antimicrobial Activity of Azoles and Azines Derivatives from Tertiary Butyl Carbazatel

Ghoneim AA and Assy MG

We synthesized a new series of heterocyclic compounds tertiary butoxy carbazone derivatives 2a-b. The synthesized compounds 1,3,4-oxadiazole derivatives 3a, 4a, 1,3-thiazolidine (5a-b), azitidin-2-one derivative (6a), pyrrolidin-2-one (7a), were achieved by the cyclization of tertiary butoxy hydrazone derivatives 2a,b with bromine in acetic acid, acetic anhydride, thioglycollic acid, chloro acetyl chloride acid and malononitrile. Also teriary butyl carbazate was reacted with isatin to afford indolylidene acetohydrazide derivative 11 which was reacted with ammonium acetate and hydrazine hydrate to 12 and 15 to give compound respectively.