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Multivariate Analysis of Trace Elements Distribution in Hair of Pleural Plaques Patients and Health Group in a Rural Area from China

Binggan Wei, Linsheng Yang, Ouyang Zhu, Jiangping Yu, Xianjie Jia, Tingrong Dong and Rongan Lu

Background: Little is known about trace metal distribution in hair of pleural plaques patients. Metals might promote the incidence of asbestos-related diseases. Therefore, the selected metals in hair of pleural plaques patients and health group from a rural area is investigated in this study.

Results: The results indicated that mean concentrations of the metals in hair usually varied between pleural plaques patients and health group. Correlation analysis showed that strong positive correlations were found between Mg-Mn, Mg-Sr, Cd-Mn, Cd-Pb in hair of pleural plaques patients, while the correlations were not obvious in the hair of health groups. Moreover, cluster analysis reveals that Mg and Sr are all strong positive correlation in both male and female.

Conclusions: It can be concluded that significantly different patterns of metal distribution in the hair of pleural plaques patients in comparison with health group. More evidences were needed to confirm that the metals are associated with pleural plaques.