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Utilization of JAK Inhibitors for the Treatment of Alopecia Areata

Reiko Noborio*

Alopecia Areata (AA) is an autoimmune disease characterized by hair loss. The degrees of hair loss include patches of hair loss on the scalp or complete scalp hair loss (alopecia totalis), complete scalp hair loss and hair loss on other body parts (alopecia universalis), and hair loss along the hairline (ophiasis). Intractable AA can negatively affect patients’ mental health and complicate their social life. Although there is no reliable and effective treatment for AA, reports of the effects of treatments comprising Janus kinase (JAK) inhibitors have accumulated.