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From “Old” Cloning to “Young” Cellular Reprogramming: Nobel Prize 2012 Spotlighted the Stem Cell Work

Yue Zhang

Here is a concise historical review and some perspectives on the spotlighted nuclear transplantation (cloning) and induced pluripotent stem cells (iPSC). Besides, we propose that iPSC may be hypothetically considered one exceptional case among “cancerous” cells. The argument between stochastic and elite model of iPSC is briefly discussed.