अग्नाशयी विकार और चिकित्सा
खुला एक्सेस

अमूर्त

सिस्टिक फाइब्रोसिस-संबंधी अग्नाशयी शिथिलता: एक स्पष्ट अन्वेषण

मैरियन रोलैंड

Pancreatic Cystic Fibrosis (PCF) is a significant manifestation of Cystic Fibrosis (CF), a hereditary disorder affecting multiple organ systems. Cystic fibrosis is an autosomal recessive genetic disorder caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, located on chromosome 7. These mutations impair the function of CFTR protein, leading to abnormal ion transport across epithelial cells and subsequent dysfunction of exocrine glands, including those in the pancreas.