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खुला एक्सेस

अमूर्त

Probiotics: A Comprehensive Review on the Impact of Gut Imuno-Modulation

Udayakumar Prithika*, Mohamed Syed Arafath

Although the host by itself develops an immune response against the invading pathogen, it is not always sufficient to get rid of the bacterium completely. Evidence indicates that gut microbiota has a major impact on host immunity. Gut is a key player in immune health which constantly gets exposed to numerous toxins. The gut microbiota comprises of more than 400 species of bacteria. This wide range of bacterial species provides a symbiotic relationship between the gut and immune cells of the body. Current research has shown the potential of probiotic in the gut health and bowel diseases. Effects of probiotics have been observed in the enhancement of both innate and adaptive immunity. While there is a considerable amount of studies on the characterization and formulation of probiotics, there is still a translational gap that owes to the challenges that confront during a disease symptom. This chapter will discuss on the fundamental issue relating to the gut health and host immune response influenced by probiotic strains.