जर्नल ऑफ़ सेल साइंस एंड थेरेपी
खुला एक्सेस

अमूर्त

Tumor Therapy with Amanita phalloides: Remission of a Tumor Disease and Dietary Effect of Sugar

Isolde Riede

Molecular events that cause tumor formation upregulate a number of HOX genes, called switch genes, encoding for RNApolymeraseII transcription factors. Thus, RNApolymeraseII is used to full extent in tumor cells but not in somatic cells. Amanita phalloides contains amanitin, inhibiting RNApolymeraseII. Application of Amanita phalloides influences tumor cell (but not normal cell) activity. Dilutions of Amanita phalloides are applied to a patient with both, colon carcinoma and thyroid carcinoma. Monitoring tumormarkers, different doses of Amanita are applied. After two years of stabilization, somatic investigations and imaging methods reveal complete remission. Change of dietary practice with the addition of daily 70 gram sugar lead to increase of tumormarker values. Following dietary without sugar and reduced carbohydrates decrease tumormarker values. With sugar, tumor activity increase despite Amanita tumor therapy, therefore, poor carbohydrate diet supports the therapy