select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='48307' and ad.lang_id='8' and j.lang_id='8' and vi.lang_id='8' The Role of T regulatory Cells (Tregs) in the Development an | 48307
क्लिनिकल और सेलुलर इम्यूनोलॉजी जर्नल

क्लिनिकल और सेलुलर इम्यूनोलॉजी जर्नल
खुला एक्सेस

आईएसएसएन: 2155-9899

अमूर्त

The Role of T regulatory Cells (Tregs) in the Development and Prevention of Type 1 Diabetes

Stavroula A. Paschou, Stelios Tigas, Katerina Naka, George K. Papadopoulos and Agathocles Tsatsoulis

In this article, we review the role of T regulatory cells (Tregs) in the development and prevention of type 1 diabetes. We first examine the definition of human Tregs, the generation of Tregs in the thymus and the periphery, their mode of action and their important role in the regulation of the immune response. We then examine the defects in Tregs observed thus far in type 1 diabetes and their role in the development of the disease. Finally, we point to possible clinical applications using Tregs as a therapeutic target for the prevention of type 1 diabetes.

अस्वीकरण: इस सार का अनुवाद कृत्रिम बुद्धिमत्ता उपकरणों का उपयोग करके किया गया था और अभी तक इसकी समीक्षा या सत्यापन नहीं किया गया है।
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