select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='50340' and ad.lang_id='8' and j.lang_id='8' and vi.lang_id='8' The Role of CD4+ T cells in the Development of an Efficaciou | 50340
क्लिनिकल और सेलुलर इम्यूनोलॉजी जर्नल

क्लिनिकल और सेलुलर इम्यूनोलॉजी जर्नल
खुला एक्सेस

आईएसएसएन: 2155-9899

अमूर्त

The Role of CD4+ T cells in the Development of an Efficacious HIV Vaccine

Haitao Liu, Wei Shen, Jiayi Shu and Xia Jin

HIV infection has caused serious public health disaster during the past three decades. The rapid discovery of antiretroviral drugs and the implementation of combination antiretroviral therapy in many countries over the past two decades have led to a marked decrease in HIV-associated mortality and morbidity. However, the antiretroviral therapy alone has been unable to eradicate the virus from HIV-infected individuals. To reduce the incidence of HIV infection on a global scale, vaccine is still the most cost-effective method. Due in part to the lack of a comprehensive understanding of immune correlates of protection, an effective HIV vaccine has not yet been developed. Since CD4+ T cells play a central role in orchestrating various arms of immune responses, vaccines that mobilize CD4+ T cells should help to elicit desired immune responses for the prevention of HIV infection. The current knowledge on subsets of CD4+ T cells and their perceived roles in mediation and formation of post-vaccination protective immunity are discussed.

अस्वीकरण: इस सार का अनुवाद कृत्रिम बुद्धिमत्ता उपकरणों का उपयोग करके किया गया था और अभी तक इसकी समीक्षा या सत्यापन नहीं किया गया है।
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