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ROLE OF FLAVONOIDS IN HUMAN NUTRITION AS HEALTH PROMOTING NATURAL CHEMICALS - A REVIEW

Rupesh kumar M , K Kavitha, S A Dhanaraj

Flavonoids are a class of secondary plant metabolites with significant antioxidant activities. There are many biological activities attributed to flavonoids. Their cardio protective effects stem from the ability to inhibit lipid peroxidation, chelate redox-active metals, and attenuate other processes involving reactive oxygen species.The majority of them could be beneficial and some of them may be detrimental, depending on specific circumstances. They are structurally similar to estrogens, exerting both estrogenic and antiestrogenic properties in various tissues. The results of epidemiologic studies exploring the role of flavonoids in human health have been inconclusive. Some studies support the notion of a protective effect of their consumption in immunomodulation, cognition, and risk reduction of certain cancers, cardiovascular and skin diseases, osteoporosis and obesity, as well as relief of menopausal symptoms. Other studies failed to demonstrate any effects.