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Pure Verrucous Carcinoma of the Penis: Two Cases

Shoichiro Mukai, Kozue Nakahara, Takahiro Nagai, Toyoharu Kamibeppu, Satoru Sugie, Hiromasa Tsukino, Toshio Kamimura, Hironobu Wakeda and Toshiyuki Kamoto

Verrucous carcinoma is a rare subtype of penile verruciform squamous cell carcinoma. However, in past literature, the diagnosis of verrucous carcinoma has been confused with giant condylomas, and papillary and warty carcinomas due to the absence of critical criteria in pathological diagnosis. We experienced two cases of penile verruciform tumor occurring in a 48-year-old Japanese male and an 88-year-old Japanese male. We performed partial penectomy without lymph node dissection after biopsy. Although we initially detected small palpablelymph node swelling in the latter case, unnecessary lymph node dissection could be avoided by pathological diagnosis using preoperative biopsy. The resected specimens were diagnosed in accordance with the World Health Organization (WHO) classification and current pathological reviews. Histopathological findings and immunohistochemical appearance were compatible with a diagnosis of verrucous carcinoma.