जर्नल ऑफ़ स्लीप डिसऑर्डर एंड थेरेपी
खुला एक्सेस

अमूर्त

Pilot Study of Oral Negative Pressure Therapy for Obstructive Sleep Apnea-Hypopnea Syndrome

Yuji Yamaguchi and Masako Kato

Background: Although the continuous positive airway pressure is the gold standard therapy for patients with moderate to severe obstructive sleep apnea-hypopnea syndrome (OSAHS), there are several treatment options
such as mandibular advancement devices, tongue-retaining devices, and nasal airway stent devices. Recently, newly developed intraoral pressure gradient therapy system, iNAP® Sleep Therapy System, was introduced as an alternative treatment for OSAHS patients.
Purpose: This feasibility study explored the effectiveness of the iNAP® device for patients with mild to moderate OSAHS.
Materials and Methods: The iNAP® device consisted of an oral interface, a tube set with a saliva container, and a negative pressure console. Negative pressure is introduced directly from the oral interface and the pressure pulls the tongue anteriorly, resulting in improving the obstruction or narrowing of the upper airway. A total of 5 male and 4 female patients with mild to moderate OSAHS, aged between 32 and 62, with 50.6 years ± 11.7 years were recruited in the study.
Results: The baseline apnea-hypopnea index (AHI) was 17.2 events per hour ± 4.7 events per hour, while AHI with the iNAP® device was 12.7 ± 5.4 (p