थर्मोडायनामिक्स और कैटलिसिस जर्नल
खुला एक्सेस

अमूर्त

Nasal Carriage Rate, Antimicrobial Susceptibility Pattern and Associated Factors of Staphylococcus aureus with Special Emphasis on MRSA among Urban and Rural Elementary School Children in Gondar; Northwest Ethiopia; A comparative cross-sectional study

Abiye Tigabu

Introduction: Staphylococcus aureus is a Gram positive, catalase positive and coagulase positive bacterial species commonly found on  the skin and in the nose of most healthy individuals. The anterior nares of nose are the most frequent carriage sites for S. aureus in  both adults and children. Methicillin resistance among S. aureus isolates has steadily increased worldwide. Objective: The main objective of this study was to determine nasal carriage rate, antimicrobial susceptibility pattern and associated  risk factors of Staphylococcus aureus with special emphasis on MRSA among urban and rural elementary school children in Gondar,  Northwest Ethiopia. Method: A community based comparative cross sectional study was conducted on 622 urban and rural elementary school  children in Gondar from January 1st to March 30th, 2018. Data was collected using a questionnaire and nasal swab samples were  collected by sterile cotton tip swab moistened with sterile normal saline. Collected samples were inoculated on mannitol salt agar and  incubated aerobically at 37oC for 24hrs. S. aureus was confirmed by observing colony characteristics and biochemical tests. MRSA was  detected using cefoxitin disc by Modified Kirby Bauer disk diffusion technique. Finally data was entered, cleared and checked using  Epi-info version 7 and exported to SPSS version 20 for analysis. Odds ratio and logistic regression were used for statistical association.  P-value < 0.05 at 95% CI was considered for statistical association.