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Multisite Atherosclerotic Disease: State of Art and Review of Literature

Paola Di Noi, Marta Francesca Brancati, Francesco Burzotta, and Carlo Trani

Multisite artery disease, defined by the simultaneous presence of atherosclerotic lesions in at least two major vascular territories, denotes an aggressive manifestation of the diseaseand leads to a deterioration of cardiac prognosis. The therapeutical strategy of multisite artery disease is not standardized and it is influenced by increased risk for both vascular and coronary surgery.

Percutaneous treatmentshould be considered as analternative to surgical revascularization in patients at high surgical risk.Simultaneous percutaneous intervention involving coronary and peripheral arteries seems to represent a promising strategy of treatment.