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Lymphoid Aggregates in Acute Myeloid Leukemia: A Case Report of Four Cases

Seema Sharma, Shrestha Ghosh and Krushna chandra Pani

Reactive Lymphoid aggregates (LA) in association with acute myeloid leukemia is an uncommon finding. We describe four cases of acute myeloid leukemia (AML) that showed lymphoid aggregates in the bone marrow biopsy. Methods and results: Detailed clinical, laboratory data and bone marrow biopsy findings were evaluated in all four cases of AML, showing LA in bone marrow biopsy. On immunohistochemistry CD20 and CD3 positivity was observed with variable intensities and patterns.