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BISPHOSPHONATES : CAN THESE BE THE BONE EATERS ?

Ajay Chhabra, Vandana Chhabra

Bisphosphonates are a group of synthetic analogs of inorganic pyrophosphate ( an endogenous regulator of bone mineralization) Bisphosphonates are a family of drugs used to prevent and treat osteoporosis, multiple myeloma, Paget’s disease (bone cancers), and bone metastasis from other cancers. These drugs can bond to bone surfaces and prevent osteoclasts (cells that breakdown bone) from doing their job.