इम्यूनोजेनेटिक्स: ओपन एक्सेस

इम्यूनोजेनेटिक्स: ओपन एक्सेस
खुला एक्सेस

अमूर्त

इटली में चल रही कोविड-19 महामारी के दौरान स्वास्थ्य कर्मियों की निगरानी का एक दीर्घकालिक अध्ययन

फ्रांसेस्को बारबेरो1, फोस्कारिना डेला रोक्का2, एंड्रिया पाडोअन3, ऐटा ए3, वीटो सियानसी2, डेनिएला बैसो3, अन्नामारिया कैटेलन1, क्लाउडिया सैंटारोसा2, मारियो प्लेबानी3, लुइगी डैल'ओल्मो4,5*

Background: Northern Italy was the first area outside China to be involved in the SARS-CoV-2 pandemic. This observational study depicts SARS-CoV-2 prevalence and serological curves among first-line healthcare workers (HCWs) at Padua University Hospital (PdUH), North East Italy.

Method: 344 first-line HCWs underwent a SARS-CoV-2 RNA nasopharyngeal swab with paired IgM and IgG antibody detection for 4 consecutive weeks and after a follow up of 5 months.

Results: Twenty-seven HCWs (7.84%) had positive serology (Abs) with 12 positive swabs during the study period. Two additional HCWs were positive by swab but without Abs. Fourteen cases (4%) had SARS-CoV-2 infection before the beginning of the study. An HCW with autoimmune disease showed false Ab results. 46% of individuals with Abs reported no symptoms. Fever, nasal congestion, diarrhoea and contacts with SARS-CoV-2 individuals correlated to SARS-CoV-2 infection. 96% of Abs+ cases showed persistent positive antibodies 5 months later and none was reinfected.

Discussion: Correct use of PPEs and separate paths for positive/negative patients in the hospital can result in a low percentage of SARS-CoV-2 infections among HCWs. Frequent testing for SARS-CoV-2 is worthwhile, irrespective of HCWs' symptoms.

अस्वीकरण: इस सार का अनुवाद कृत्रिम बुद्धिमत्ता उपकरणों का उपयोग करके किया गया था और अभी तक इसकी समीक्षा या सत्यापन नहीं किया गया है।
Top